Research Group

Liver Cell Biology

(Brussels Health Campus - Vrije Universiteit Brussel)

Objectives

In general, research projects at LIVR aim to better characterize the different liver cell types in healthy and pathological conditions, and to gain a better insight in the mechanisms of liver regeneration and the pathogenesis of liver fibrosis.

The LIVR team investigates:

  • the mechanisms of liver fibrosis development and resolution
  • the identification of hepatic stellate cell-specific biomarkers for liver fibrosis staging
  • the generation of in vitro liver disease models
  • iPSC derived liver cells for in vitro disease modeling
  • the role for liver progenitor cells during liver regeneration

Long term objectives are:

  • Contribute to the understanding of mechanisms involved in liver fibrosis
  • Discover therapeutic targets for chronic liver diseases including non-alcoholic fatty liver disease (NAFLD).
  • Develop in vitro models representative for human chronic liver disease

Events

EASL

EASL 2019: The International Liver Congress (10-14 /04/2019)

From 10 April at 8:00 to 14 April at 18:00

BWGE-2018

31st Belgian Week of Gastroenterology (20-22/02/2019)

From 20 February at 9:00 to 22 February at 17:00

BSSCR-5

5th Annual Meeting of the Belgian Society for Stem Cell Research (26/10/2018)

26 October from 9:00 to 17:00

Stem Cells: From Fundamental Discoveries To Life Saving Clinical Treatments

October 2019

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Team Members

LIVR 2019

Research

Research

FACSAria-BDThe LIVR laboratory offers Flow Cytometry Service, using a BD FACSAria cell sorter (2006, first generation, upgraded to FacsAria IIu in 2014). The system has 3 lasers for excitation: UV-laser (355nm), Blue laser (488nm) and Red laser (633nm) and 11 fluorescence detectors. We offer support for the experimental setup, operation of the system and analysis of data using FlowJo software.

The LIVR team was partner in the Seurat-1 cluster (EU-FP7 programme 2011-2015)