Prospects in non-invasive assessment of liver fibrosis: Liquid biopsy as the future gold standard?

  • January 9, 2018
Biochim Biophys Acta. 2018 Apr;1864(4 Pt A):1024-1036. doi: 10.1016/j.bbadis.2018.01.009. Epub 2018 Jan 9.

 

Highlights

  • Early diagnosis and step-wise follow up of liver fibrosis is needed.

  • Current non-invasive diagnostic tools lack sufficient sensitivity and specificity.

  • Liquid biopsy might overcome current diagnostic limitations.

  • Circulating vesicles and free nucleic acids, proteins, and lipids as biomarkers

  • Limitations and possibilities of liquid biopsy in liver fibrosis